As the 2026/27 Serie A season kicks off, Cagliari hosts Roma at Unipol Domus for matchday 38. With both teams entering the match with no prior form this season, it’s a fresh start for both sides, eager to make their mark. Interestingly, there are no recorded head-to-head meetings between the two, making this encounter even more intriguing. The anticipation is palpable as fans look forward to seeing how both squads will perform in this opening fixture. With the community split on predictions, it’s anyone’s guess how the match will unfold. Will Cagliari capitalize on home advantage, or can Roma make a strong impression on their travels? Get ready for an exciting clash as the new season begins. Don’t forget to predict the score on TrendyAlpha!